Neurology: Clinical Studies Open for Enrollment
Responsive Stimulation for Adolescents with Epilepsy (RESPONSE) Study
Eligibility
- Patient is between 12-17 years of age
- Disabling motor simple partial seizures, complex partial seizures and/or secondary generalized seizures
- Seizures that are distinct, stereotypical event that can be reliably counted
- Subject had an average of three or more disabling seizures and/or generalized seizures over the two most recent consecutive 30 days.
- Subject failed treatment with a minimum of 2 AED (anti-epileptic drugs)
Enrollment Status: Actively enrolling
Study Information
ClinicalTrials.gov | NCT04839601
Principal Investigator
Steven Wolf, MD
Contact for Study Screening
ppena_ar@nymc.edu
dzogejan@nymc.edu
Eligibility
- Male or female, Aged ≥18 years on the index date
- Admitted to the hospital with an acute major bleeding or developed an acute bleeding while already in hospital
- Ongoing treatment with a Factor Xa inhibitor before the index date
- Provided signed and dated informed consent or able to obtain a waiver
- In addition, for cohort B:
- Administered reversal or replacement therapy
- Exclusion Criteria
- Pregnant women
- Patients enrolled in any interventional trial that includes reversal/replacement agents
- In addition, for cohort B:
- Use of vitamin K antagonists, dabigatran, prothrombin complex concentrates or recombinant factor VII, or transfusion of whole blood or plasma within the preceding 7 days of the index event
- As judged by the investigator, if it is deemed undesirable for the patient to participate in the study or participant is unlikely to comply with study procedures, and requirements
- Involvement in the planning and/or conduct of the study
Enrollment Status: Actively enrolling
Study Information
ClinicalTrials.gov | NCT06147830
Principal Investigator
Carolin Dohle, MD
Contact for Study Screening
Cristina.Falo@wmchealth.org